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Ochronosis

Etymology:

Gr. ōkhrós: “pale yellow, sallow” + Gr. nósos, “sickness, disease, plague”

Definition:

Abnormal brown pigmentation (reflecting the histological finding of yellow-brown deposits in the dermis) of tissue (especially cartilage and ligaments) resulting from the accumulation of a melanin-like pigment derived from homogentisic acid in the metabolic disorder/disease alkaptonuria.

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